Time-Resolved Single-Step Protease Activity Quantification Using Nanoplasmonic Resonator Sensors
نویسندگان
چکیده
منابع مشابه
Time-resolved single-step protease activity quantification using nanoplasmonic resonator sensors.
Protease activity measurement has broad application in drug screening, diagnosis and disease staging, and molecular profiling. However, conventional immunopeptidemetric assays (IMPA) exhibit low fluorescence signal-to-noise ratios, preventing reliable measurements at lower concentrations in the clinically important picomolar to nanomolar range. Here, we demonstrated a highly sensitive measureme...
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ژورنال
عنوان ژورنال: ACS Nano
سال: 2010
ISSN: 1936-0851,1936-086X
DOI: 10.1021/nn900757p